Introduction
Hidradenitis Suppurativa (HS) is a chronic inflammatory skin condition that extends far beyond its physical symptoms. Painful nodules, recurrent flare-ups, and long-term scarring are often the most visible effects of HS, but what remains unseen can be equally profound. The psychological and emotional toll of living with this condition is immense, affecting confidence, relationships, and overall quality of life. Many individuals with HS experience depression, anxiety, and social isolation due to the constant challenges that come with managing the disease. Understanding these mental health effects is essential to ensure that support systems, medical professionals, and the wider community can respond with empathy and practical solutions.
The Emotional Burden of Living with HS
“Living with HS can feel overwhelming due to the unpredictability of flare-ups and the pain that comes with them. The condition often develops in areas of the body that are difficult to conceal, which can lead to feelings of embarrassment and frustration. The emotional burden is compounded when individuals feel misunderstood or judged by those who do not fully grasp the seriousness of the condition. As a result, self-esteem can decline over time, and daily life may become overshadowed by worries about appearance, discomfort, and stigma. The psychological weight of constantly anticipating the next flare can be just as draining as the physical pain”. Says Chris Mansi, CEO, Viz.ai
Depression and HS
“Depression is one of the most significant mental health concerns associated with HS. Persistent pain, physical limitations, and scarring often create a sense of hopelessness. For many, the chronic nature of the disease makes it difficult to maintain optimism, especially when symptoms interfere with work, education, or personal goals. Studies have shown that people with HS are at a higher risk of depression compared to the general population. This highlights the importance of mental health screening as part of routine care for HS patients. Left unaddressed, depression can worsen quality of life and even hinder adherence to treatment plans, making the condition harder to manage”. Says Shamsa Kanwal, M.D, Consultant Dermatologist, myhsteam
Anxiety in Daily Life with HS
“Anxiety is another major challenge faced by those living with HS. The fear of sudden flare-ups can lead to constant worry, while concerns about odor, drainage, or visible symptoms may create heightened social anxiety. Many individuals find themselves planning daily activities around the possibility of pain or discomfort, avoiding certain events, or hesitating to pursue new opportunities. This constant state of alertness not only affects mental well-being but can also disrupt sleep, reduce productivity, and increase feelings of exhaustion. When anxiety becomes a daily companion, it can be as limiting as the physical symptoms of HS themselves”. Says Ashley McEvoy, President, Insulet Corporation
The Role of Social Isolation
“HS often pushes individuals into isolation. The stigma associated with visible skin conditions can lead to withdrawal from social interactions, even with close friends and family. Some may avoid gatherings out of fear of being judged or questioned about their symptoms. Others may limit physical intimacy due to pain or self-consciousness, which can strain relationships. This withdrawal can quickly lead to loneliness and deepen feelings of depression and anxiety. The absence of social support can also make it harder to cope with the condition, creating a cycle where isolation feeds mental health struggles, and those struggles reinforce further isolation”. Says Anish Bafna, CEO, Healthium Medtech
The Impact on Relationships and Identity
“Beyond general isolation, HS can have a profound effect on how individuals view themselves and their relationships. The condition may lead to changes in body image, leaving individuals struggling with feelings of shame or inadequacy. Romantic relationships can be particularly challenging, as concerns about physical appearance, intimacy, or misunderstandings about the disease may create barriers. Friendships and family connections may also suffer if others do not fully comprehend the seriousness of the condition. Over time, this can reshape a person’s identity, making them feel defined by their illness rather than their strengths and aspirations”. Says Laura Schulz, CEO, Ghost Productions
Coping Strategies for Mental Health Challenges
“While HS poses undeniable challenges, there are coping strategies that can help alleviate some of the mental health impacts. Professional therapy can provide tools to address depression and anxiety, offering a safe space to process emotions and develop resilience. Support groups, both online and in-person, allow individuals to connect with others who share similar experiences, helping reduce feelings of isolation. Self-care practices such as mindfulness, journaling, and gentle physical activity can also contribute to improved mental well-being. Importantly, communication with healthcare providers about mental health should be prioritized alongside physical treatment to ensure a holistic approach to care”. Says Vikram Thaploo, CEO, Apollo TeleHealth Services
The Importance of Awareness and Support
“Raising awareness about the mental health challenges associated with HS is essential for fostering understanding and reducing stigma. When society recognizes that HS is more than a skin condition, it creates room for compassion and support. Employers, educators, and communities can play an important role by accommodating the unique challenges that individuals with HS face. Mental health professionals and medical providers must also collaborate to ensure that patients receive integrated care. By addressing both the physical and psychological aspects of HS, the path toward improved quality of life becomes clearer and more attainable”. Says Tom Lango, CFO, Greenway Health
Moving Toward a Better Future
“The intersection of HS and mental health highlights the urgent need for comprehensive care and increased awareness. Depression, anxiety, and social isolation are not side effects to be overlooked; they are central challenges that deserve attention and action. Moving forward, advances in treatment, stronger support networks, and open conversations about the emotional realities of HS can bring meaningful change. A future where individuals living with HS feel understood, supported, and empowered is possible, but it requires a collective commitment to breaking down stigma and prioritizing mental health as part of every care journey”. Says Eva Fong, CFO, WELL Health Technologies
Conclusion
Hidradenitis Suppurativa affects more than the body; it impacts the mind, identity, and relationships of those who live with it. The struggles of depression, anxiety, and social isolation can be overwhelming, but they are not insurmountable. With greater awareness, accessible resources, and stronger support systems, individuals can find hope and resilience even in the face of challenges. Recognizing the mental health impact of HS is the first step toward creating a compassionate environment where no one feels alone in their journey.